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Invited Professors

Huai L. Feng

 

 

 doctorf88@gmail.com

 

Education

2006                      MBA, Health Service Management and Hospital Administration, Frank G.ZarbSchoolof Business,

                                Hofstra University, NY

1992                      Ph.D.  Embryology, Department of Bioengineering, Northeast Agriculture University, Harbin, China

1987                      M.S.  Embryology, Department of Histology and Embryology, University of Military Material of

PLA, Changchun, China (Present:  Jilin University)

1984                      DVM. Jilin University, Changchun, China

 

Licensure and Certification

1997-                     American board certification of High Complexity Laboratory Director (HCLD) and Embryology

Laboratory Director (ELD),Andrology Laboratory Director (ALD) , American Board of Bioanalysis, USA.

1997-                     American board certification of Technical Supervisor, American Board of Bioanalysis

1997-                     American board certification of Embryology, American Board of Bioanalysis.

1997-                     American board certification of Andrology, American Board of Bioanalysis.

2012-                     American board certification of clinical consultant, American Board of Bioanalysis.

2000-                     The Certificate of Qualification (CQP9496) as a Clinical Laboratory Director in Andrology and Endocrinolgy specialty, New York State Department of Health, NY.

2000-                     Tissue Bank Director for Oocytes/Embryos and Male Reproductive Tissues donors and Client- Depositors, New York State Department of Health, NY.

2001-                     The Certified Inspector for Laboratory Accreditation Program byCollegeofAmericanPathologists, IL,USA.

2007-                     Clinical Laboratory Technologist, Registration Certificate, The University of the State of New York, Education Department, Office of the professions. (Number#: 6087858)

2011-                  Clinical Laboratory Improvement Amendments (CLIA) , Laboratory Director       

 

Academic Appointments

1987-1989            Assistant Professor (Lecturer), Jilin University, Changchun, China

1992-1993           Associate Professor and Director, Laboratory of Embryo Technology, Jilin University, Changchun, China

1993-1995            Fellow, Center for Reproductive Science, Northwestern University, Chicago, IL.

1995-1998         Assistant Professor (Scientist), Departments of Urology and Ob/Gyn, University of Iowa Hospitals and Clinics, Iowa City, IA.

1998-                     Associate Professor, Department of Ob/Gyn, NYU School of Medicine, Manhasset, NY, USA

2009-                     Associate Professor, Department of Ob/Gyn, Hofstra University School of Medicine, NY, USA.

2011-                     Clinical Professor, Weill Cornell Medical College, Cornell University, NY, USA.

2011-                    Clinical Professor, Department of Obstetrics and Gynecology, the University of Texas Southwestern       

                            Medical Center at Dallas, TX, USA.

 

 

Professional Appointments

1998-1999            Laboratory Director, Fertility (IVF and Andrology) / Reproductive Endocrinology Laboratories, Department of Ob/Gyn, the Brooklyn Hospital Center, NYU School of Medicine, Brooklyn, NY, USA.

1999-2011            Director of Infertility and Embryology Laboratories, Department of Ob/Gyn, North Shore University

Hospital, NYUSchoolofMedicine,Manhasset,NY

1999-2011            Assistant directors, North Shore University Hospital Core Laboratories, Manhasset, NY

2004 -2006           Laboratory Director (off-site), Downtown Fertility of New York, New York, NY,USA.

2002-2011            Laboratory Director (off-site), Gold Coast IVF, Syosset, NY, USA

2000-2009            Laboratory Director (off-site), Staten Island Fertility Center, Staten Island, NY, USA

2008-                     Laboratory Director, New York Fertility Center, New York Hospital Queens, Weill Cornell Medical College, Cornell University, NY, USA

2011-                    Scientific Director, New York City IVF Center, New York, NY

2011-                   Director, IVF Laboratory, Department of Obstetrics and Gynecology, the University of Texas     Southwestern Medical Center at Dallas.

 

Awards and Honors

1985-1993            Twenty-eight scientific and technological awards from State Nature Sciences and

  Technology Committee and State Medical Ministry, China

1992                      “Outstanding young scientist” title, PLA and National Sciences Association, China

1994                      Fellowship awards, Mellon Foundation,USA

1998                        Young Scientific awards from Society for Male Reproduction and Urology, USA.

2005                     The Leading Scientists of the World 2005, IBC,Cambridge,UK.

2006                      Awarded the outstanding inspectors for 2006 from College of American Pathologists (CAP).

 

Honor Academic Titles

2002                      Honor Professor, Department of Ob/Gyn, Shandong Province Hospital, Jinan, China

2004                      Guest Professor, Shandong University, Jinan, China

2005                      Guest Professor, Inner Mongolia University, Huhhot.

2006                      Visiting Professor, the ChineseUniversityofHong Kong, HK

2007                      Guest Professor, Anhui Medical University, Anhui, China.

2008                      Visiting Professor and Guest Professor, Peking University Third Hospital, Beijing, China

2009                      Adjunct Professor, Jilin University, Changchun, China

  2011                     Guest Professor, Zheng Zhou University First and Third Hospital, Zheng Zhou, China

  2012                 Distinguished Professor, Guangzhou Traditional Medicine University, Guangzhou, China

  2012                     Guest Professor, Xinjiang Medical University, China

 

Selected Invited Lectureships

2013   Beijing ART Conference

2012       Hsiang-ya Medical College (Central South University (CSU)

2012       ASPIRE, Osaka, Japan

  2012  Zhengzhou University Lecture

2012      Infertility Meeting: From theory to practice.  Guangzhou

2012       Sixth Reproductive Medicine Annual Meeting of China, Beijing

2011       American Society for Reproductive Medicine

2011       The 4th International Workshop on Repeated Failure of IVF-ET, Guangzhou

2011    Progress in female reproduction endocrinology and immunology and infertility-The new progress Classes. Lanzhuo

2011      The first Zhengzhou International Symposium on Advancement of Assisted Reproductive Medicine, Zhengzhou

2010       The 12th ART Workshop, Chongqing

2010       American Society for Reproductive Medicine

2010       IFFS, Munich, Germany

2010        Xinjiang ART Workshop, Urumqi

2010        International Symposium on Standization of Infertility Clinical Pathway and ART, Beijing

2009        American Society for Reproductive Medicine

2009        The 11th  ART Workshop, Chongqing

  2009       Beijing District ART Meeting

2009        Women and Infant Hospital, Guangzhou

2009        American Society of Andrology (ASA)

2009      Academy Science of China, Beijing

2009      Symposium of Reproductive Medicine, Sanya, China

2008      The 10th  ART Workshop, Chongqing, China

2008      Society for the Study of Reproduction (SSR), Hawaii, USA.

2007      American Society for Reproductive Medicine, Washington DC.

2007      International Young Scientist Forum  for Reproductive Biotechnology, USA

2007      Symposium on Reproductive Medicine-Genetics in Reproduction, Suzhou

2006      The Chinese University of Hong Kong

2006      Workshop of human IVF Practice and Theory, Anhui, Hefei, China.

2006      IETS, Orlando, FL.

2005       American Society for Reproductive Medicine, Montreal, Canada

2005      SSR, Quebec, Canada.

2005      Society for the Study of Reproduction (SSR), Quebec, Canada.

2004      30th  International Young Scientist Forum on Modern Reproduction Biology, Huhhot, China.

2004      “Clinical application of PGD” (main section speaker was Sponsored by Organon) in the Workshop on Reproductive Medicine of Mainland China, Jinan, China

2004    American Society for Reproductive Medicine, Philadelphia, PA, USA

2003      Conference on reproduction medicine, Hongkong, China.

2002       Workshop on Reproductive Medicine of Mainland China, Chongqing, China

2001      American Society for Reproductive Medicine, Orlando, FL.,USA

2000       American Society for Reproductive Medicine, San Diego, USA

2000      First Workshop on Reproductive Medicine of Mainland China, Hongkong and Taiwan, Zhuhai, China

1999      American Society for Reproductive Medicine, Naples, FL. USA

1998       “Altered c-kit expression in the sperm of subfertile men”, IFFS,San Francisco,CA,USA.

1998       American Society of Andrology, Long Beach, CA, USA.

1998      Institute of Zoology, Academia, Beijing, China

1998      American Urological Association, Inc., San Diego, CA, USA.

1997      International Embryo transfer Society, Nice, France.

1997       9th international Congress of genes, Gene Families and Isozymes, San Antanio, TX, USA.

1997      Society for the Study of Reproduction, Portland, OR, USA.

1996      Society for the Study of Reproduction, London, Ontario, Canada.

1996      International Embryo transfer Society, Salt City, UT, USA.

1995      the International Embryo transfer Society, Canada.

1995       Mellon Reproduction Biology Center, NC, USA

1994      International Embryo transfer Society, Melbourne, Australia.

1993      American Animal Science Symposia, USA.

1992      International Embryo transfer Society, UT, USA.

 

Research Interest:

·         Gametogenesis, oocyte maturation and age, sperm function, and fertilization biology

·          Early embryo development and regulation

·         Stem cells

·         Genetic, Epigenetic and Imprinting

·         ART and its safety

 

Bibliography:

 

A.  Selected Book and/or Chapters Publications:

Li, Yuan, Feng, HL, Cheng, Zijiang, Assisted Reproductive Technology in Human, Beijing Scientific Publishing House,

      2008

Feng, H.L. (1994) Embryo Technology in Mammalian, The Serial Books Written by Young

Scientists, Jilin Science and Technology Publishing House,Changchun,China, pp1-320.

 

B.  Selected Paper Publications or in Press (From more than 200):

Qiao J, Wang ZB, Feng HL, Miao YL, Wang Q, Yu Y, Wei YC, Yan J, Wang WH, Shen W, Sun SC, Schatten H,   

     Sun QY.  The root of reduced fertility in aged women and possible therapentic options: Current status and future     

     perspects, Mol Aspects Med. 2013 Jun 21. [Epub ahead of print]

   Wang XM, Zhang Z, Tsai T, Feng HL. (2013) Impact of Gonadotrophins on Oocyte Maturation, Fertilization and 

     Developmental Competence in vitro: Animal Model. Reprod Fertil Dev. 2013 Jun 3. [Epub ahead of print]

Liu N, Ma Y, Li R, Jin H, Li M, Huang X, Feng HL, Qiao J. (2012) Comparison of follicular fluid amphiregulin and EGF concentrations in patients undergoing IVF with different stimulation protocols. Endocrine. 2012 Dec;42(3):708-16.

Wang XM, Feng, H. L. (2012) How to Achieve the best ART pregnancy rate via sperm selection. J. Int. Reprod Health. 31:373-377

Hu WH, Mechesi D, Qiao J, Feng HL. (2012) Effect of slow freeze verus vitrification on the oocyte: An animal  model. Fert. Steril. 98:752–60.

Marchesi D., Feng, H.L., Qiao.J. (2012) Embryo Manipulation and Imprinting, Seminars in Reprod Medicine,

     30:323-334.

Liu S, Feng, HL.  (2011) Effect of gonadotropins on dynamic events and global DNA methylation during in vitro maturation

     of oocytes: an animal model, Fertil Steril. 95(4):1503-1506.e3. Epub 2010 Nov 10.

Qiao J., Feng, H.L. (2011)Extra- and Intra-ovarian Factors in Polycystic Ovary Syndrome (PCOS): Impact on Oocyte Maturation and Embryo Developmental Competence. Human Reproduction Update, 17 (1): 17-33.

Liu S, Li Y, Feng HL, Yan JH, Chen ZJ (2010) Dynamic Modulation of Cytoskeleton During In Vitro Maturation in Human

Oocytes. Am J Obstet Gynecol. 203:151.e1-7.

Marchesi D, Biederman H, Hershlag A, Feng HL (2010) Effect of semen processing on sperm DNA integrity: Comparison of two techniques using a novel Toluidine Blue assay. European Journal of Obstetrics & Gynecology

    And Reproductive Biology 151 (2010) 176–180

Sha W, Xu BZ. Li M, Liu D, Feng HL*, Sun QY.  (2010) Impact of Gonadotrophins on Oocyte Maturation in vitro: An Animal Model. Fertility and Sterility, 93:1650-61.

Feng H L. (2009) Spermatozoa defect and Fertilization Failure. J Reprod. Med. 18(3):187-189.

Han YB, Feng HL, Sandlow, J, Haines C. (2009) Comparing expression of progesterone and estrogen receptors in testicular tissue from men with obstructive and non-obstructive azoospermia, J. Andrology., 30:127-133.

Feng HL. Han YB, Sparks AET, Sandlow JI (2008) Characterization of Human Sperm Antigens Reacting with

Antisperm Antibodies from an Infertile Female Patient’s Serum. J Androl. 2008 Mar 20;29:440–448

Feng HL, Hershlag A, Scholl GM, Cohen M. (2009) A retroprospective study comparing four different assisted hatching techniques. Fertility and Sterility, 91:1323-5.

Marchesi DE, Feng HL (2007) Current assessment of sperm DNA integrity, Archives of Andrology,

53:239-247.

Marchesi D.E and Feng , HL. (2007) Sperm DNA Integrity from Sperm to Egg, Journal of Andrology, 28(4):481-489. Feng, H.L., Han, Y.B., Hershlag, A, Zheng, LJ. (2007) The Impact of Ca2+  Flux Inhibitors on Acrosome Reaction of

Hamster Spermatozoa, J. Andrology, 28(4):561-4.

Feng, H.L., Hershlag, A., Han, Y.B., Zheng, L.J. (2006) Localizations of intracellular calcium and Ca2+-ATPase in hamster spermatogenic cells and spermatozoa, Microscope Res. Tech. 69:618-623.

Feng, HL. Han, Y.B., Hershalg, A., Yang, H. (2006) New Hope for Infertility Therapy: Fabricating Gametes from

      StemCells, Arcives of Andrology., 52:233-8.

Chen, Z.J., Yuan, J.H., Feng, H.L. (2005) Source of the extra pronucleus after intracytoplasmic sperm injection?

Fertility and Sterility,  84(5):1553-1554.

Herhlag A., Feng, H.L. (2005) Impact of medium pH on murine embryogeneis,  Fertility 4:21-22.

Li, Y., Feng, H.L., Cao, Y.J., Ma, S.Y., Li, M., Hu, J.M., Chen, Z.J. (2006) Confocal Microscopy Analysis of the

Spindle and Chromosome Configurations of Human Oocytes Matured in vitro. Fertility and Sterility, 85(4):827-

32.

Hershlag, A., Feng, H.L. (2005) The Effect of Pre-Freeze Assisted Hatching on Post-Thaw survival of mouse embryos, Fertility and Sterility,  84(6):1752-1754.

Chen, Z. J., Yan, J.H., Feng, H.L. (2005) Aneuploid Analysis of tripronuclear zygotes derived from in-vitro

fertilization and intracytoplasmic sperm injection in human, Fertility and Sterility, 83:1845-8.

Feng, H.L., Sandlow, J.I., Zheng, L.J. (2004) The c-kit receptor and its possible function in human spermatozoa,

 Molecular Reproduction and Development, 70:103-110.

Chen, Z. J., Li, M.,  Li, Y., Feng, H.L. (2004) Effects of Sucrose Concentration on the Developmental Potential of

Human Frozen-Thawed Oocytes at Different Maturity Stages, Human Reproduction, 19(10 ):2345–2349.

Xu, H.P., H.L. Feng (2004) Localization and expression of the TSP50 protein in human and rodent testis, Urology,

64 (4):826-832

Feng, H.L., Hershlag, A. (2003) Fertilization abnormalities following human in-vitro fertilization and

intracytoplasmic sperm injection,  Microsc Res Tech., 61(4):358-61.

Hershlag, A., Feng, H. L. (2003) Betadine (povidone-iodine) is toxic to murine embryogeneis , Fertility and Sterility, 79(5):1249-1250.

Feng, H. L. (2003) Molecular Biology of Male Infertility, Archives of Andrology, 49:19-27.

Hershlag, A., Pain, T, Kvapil, G., Feng, H.L. (2002) In vitro fertilization-intracytoplasmic sperm injection split: an insemination methos to prevent fertilization failure, Fertil. Steril. 77:229-32.

Feng, H.L., Sandlow, JI.,Sparks, AET. (2001) Decreased expression of the heat shock protein hsp70-2 is associated

with the pathogenesis of male infertility, Fert. Steril. 76:1136-1139.

Feng, H.L., Sandlow, JI.,Sparks, AET., Sandra, A., Zheng, LJ. (1999) Decreased expression of the c-kit  receptor

is associated with increased apoptosis in subfertile human testes, Fertil. Steril. 71:85-89.

Feng, H.L., Sandlow, JI., Sandra, A.,Sparks, AET. (1999) Development of Immunocontraceptive vaccine:

current status, J. Reprod. Medicine. 44:759-765.

Feng, H.L., Sandlow, J.I. and Sandra, A. (1998) Presence of c-kit receptor and its possible signaling

pathway in mouse sperm, Mol. Reprod. Dev. 49:317-326.

Sandlow, J.I., Feng, H.L. Zheng, L.J.and Sandra, A. (1999) Migration and localization of the c-kit receptor protein in

spermatogenetic cells and spermatozoa of the mouse, J. Urology, 161:1676-80.

Sandlow, J.I., Feng, H.L. and Sandra, A. (1997) Localization and expression of the c- kit receptor protein

in human and rodent testis and spermatozoa, Urology., 49:494-500.

Feng, H.L., Sandlow, J.I. and Sandra, A (1997) Expression and function of the c-kit proto-oncogene

protein in mouse sperm, Biol. Reprod. 57: 194-203.

Feng, H.L., Wen, X.H., Theodore, A., and Presser, S.C. (1996) Effect of different coculture systems in

early human embryo development, Human Reproduction., 11:1525-1528.

Sandlow, J.I., Feng, H.L. and Sandra, A. (1996) Expression of c-kit and its ligand, stem cell factor, in

normal and subfertile human testicular tissue, J. Andrology,  17:403-408.

Sun Q.Y.  Yang Q.Z. Liu G.Y. Feng H.L (1995) Cryopreservation of bovine oocytes matured in vitro, Theriogenology, 43:329-330.

Feng, H.L., Yang, Q.Z., Sun, Q.Y., Qin, P.C. and Liu, J.M. (1994) Development of early bovine embryos in different culture systems, Vet. Rec., 135:304-306.

Feng, H.L., Liu, J.M., Wen, X.H., Wang, J., Sun, Q.Y. and Qin. P.C. (1994) Follicular oocyte maturation

and sperm penetration in vitro in the silver fox (vulpes vulpes),  Anim. Reprod. Sci., 36:163-170.

Feng, H.L. and Sun, Q.Y. (1995) Cryopreservation of bovine oocytes matured in vitro, J. Anim.

Sci. Vet. Med., 26:481-486.

Feng, H.L. and Sun, Q.Y. (1994) Development competence of bovine follicular oocytes after cryopreservation,  J. Vet. Sci., 

    14:341-345.