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XinJie Zhuang

Xin-Jie ZHUANG , Ph.D. Research associate
Subject: Developmental Biology and IVF
Tel: 86-10-82265045
E-mail: zhuangxinjie902@163.com

Zhuang received His Ph.D. degree in the College Animal Science & Technology, Guangxi University in 2011. After graduating, he was working as a research associate in Reproductive Medicine Center, Peking University Third hospital. Currently, his major research interest is to study the mechanisms of spermatogenesis, oogenesis, oocyte maturation and fertilization by using methods of bioinformatics, molecular biology and cell biology. His funding supports are from the National Natural Science Funding Committee. He have published papers in “Cell Cycle”, “Gene”, “PLoS One”, “Reproduction, Fertility and Development”, “Reproduction in Domestic Animals”, “Animal Reproduction Science” and other journals.

Education and Training:
2008/09-2011/05, Institute of Zoology, Chinese Academy of Sciences, Ph.D.
2005/09-2011/05, Animal Reproduction Institute, Guangxi University, Ph.D.
2005/09-2008/07, Animal Reproduction Institute, Guangxi University, Master
2003/09-2005/07, Animal science, Henan Agriculture University, Bachelor

2011/05-- , Reproductive Medicine Center, Peking University Third hospital.

Selected Publications:
1.Zhuang XJ, Shi YQ, Xu B, Chen L, Tang WH, Huang J, Lian Y, Liu P, Qiao J. SLX2 interacting with BLOS2 is differentially expressed during mouse oocyte meiotic maturation.Cell Cycle. 2014;13(14):2230-6.  (Impact Factor: 5.006).
2.Shi YQ1, Zhuang XJ1, Xu B, Hua J, Liao SY, Shi Q, Cooke HJ, Han C. SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60. Gene. 2013;527(1):352-9. (1Co-author, Impact Factor: 2.196).
3.Xin-jie Zhuang, Yi Huang, Ya-ping Duan, Yang-qing Lu, Ming Zhang and Ke-huan Lu. Translocation of active mitochondria during buffalo (Bubalus bubalis) oocytes in vitro maturation, fertilization and preimplantation embryo development. Reproduction in Domestic Animals, 2012 Jun;47(3),443-448. (Impact Factor: 1.392).
4.Xin-jie Zhuang, Xiao-jun Hou, Shang-ying Liao, Xiu-Xia Wang, Howard J Cooke, Ming Zhang, Chun-sheng Han. SLXL1, a novel acrosome protein, interacts with DKKL1 and is involved in fertilization in mice. PLoS One. 2011; 6 (6): e20866. (Impact Factor: 4.092).
5.Xin-jie Zhuang, Yang-qing Lu, Ming Zhang, Sheng-sheng Lu and Ke-huan Lu. Microisolation and microcloning of bovine sex chromosomes for sexing sorted buffalo (Bubalus bubalis) spermatozoa. Animal Reproduction Science. 2011; 126(1-2):32~36. (Impact Factor: 1.897).
6.Hu C H, Zhuang X J, Wei Y M, Zhang M, Lu S S, Lu Y Q, Yang X G, Lu K H. Freezing procedure can result in more serious apoptosis of boar spermatozoa than bull spermatozoa. Reproduction in Domestic Animals. 2011, 46(2) :93~93. (Impact Factor: 1.392).
7.M Zhang, X J Zhuang, Y Q Lu, C H Hu, S S Lu, K H Lu. Identification of  X- and Y-bearing spermatozoa in sorted buffalo (Bubalus bubalis) semen by fluorescence in situ hybridization. Reproduction, Fertility and Development, 2009, 21(1) :231~232. (Impact Factor: 2.583).
8.Yu-Qiang Shi, Shang-Ying Liao, Xin-Jie Zhuang, Chun-sheng Han. Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37.Gene. 2011 Oct 10; 485(2):153~159. (Impact Factor: 2.196).
9.Tang WH, Liu DF, Jiang H, Ma LL, Hong K, Zhao LM, Mao JM, Yang Y, Zhang J, Gao L, Zhuang XJ, Qiao J. Assisted semen collection using two phosphodiesterase type 5 inhibitors (Tadalafil and Sildenafil) in infertile men with mild erectile dysfunction. Chin Med J (Engl). 2013;126(14):2788-9.  (Impact Factor: 0.901).
10.Xin-jie Zhuang, Ya-ping Duan, Yi Huang, Shu-fang Ning, Ming Zhang.Culture and Biological Characteristic Analysis of stromal and glandular epithelial cells of buffalo(Bubalus bubalis)endometrium. Agricultural Science & Technology, 2009, 10 (3): 39~42,71.